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The AASLD/IDSA guidance recommends using the same approach for HCV treatment in persons coinfected with HIV as those with HCV monoinfection, but noting that important drug-drug interactions between HCV medications and HIV antiretroviral medications need to be recognized and managed. In the HCV guidance,
6 Feb 2012 Alternatively, the HIV-HCV International Panel and the European AIDS Clinical Society have recommended treatment guidelines for PEG-IFN and RBV with more flexible durations than those in the U.S. guidelines, based on genotype and virologic response to therapy at week 4 (rapid virologic response
Up-to-date information about approved and experimental therapies for HIV/AIDS, Hepatitis, and related conditions.
14 Jul 2016 Last updated March 27, 2012; last reviewed March 27, 2012) Key Considerations When Managing Patients Coinfected with HIV and Hepatitis C Virus: Rating of Recommendations: A = Strong; B = Moderate; C.
patients coinfected by HCV and HIV, as well as in hepatitis B virus (HBV)/HIV-coinfected patients. (1), despite the availability of treatments with proven efficacy (2–5). Most patients are, however, not treated, underscoring the need for treatment guidelines. Efforts must also be made, via multidis- ciplinary health-care services,
17 Oct 2017 Initial ARV combination regimens recommended for most HIV treatment-naive patients with HCV are the same as those recommended for patients without HCV infection. HBV reactivation has been observed in persons with HBV infection during interferon-free HCV treatment.
21 Sep 2017 The combination of daclatasvir and sofosbuvir once daily for 12 weeks achieved SVR12 in 97% of HIV/HCV-coinfected patients with genotype 1, 2, 3, or 4 infection, and was safe and well tolerated. Ninety-seven percent of treatment-naive patients and 98% of treatment-experienced patients achieved SVR.
The following recommendations (Table 1) emphasize management and treatment issues specific for the HIV/HCV-coinfected patient. Recommendations are graded according to those used by the American Association for the Study of Liver Disease (AASLD) practice guidelines for the diagnosis, management, and treatment

8 Sep 2017 The consequences of hepatitis C virus (HCV) infection in HIV-infected patients are significant and include accelerated liver disease progression, high rates (See "Clinical manifestations, diagnosis, and treatment of acute hepatitis C virus infection in adults".) GUIDELINES. Guidelines for the diagnosis and